General Molecular Technologies

Thursday, November 16, 2017


7:00am - 8:00am


Standardization of Projects in Pharmacogenetics

AMP CYP2C19 PGx Variant Standardization Project
Victoria M. Pratt, PhD, Indiana University, Indianapolis, IN, USA

PGx  Standardization Project
Steven A. Schichmann, MD, PhD, John L. McClellan Memorial Veterans Hospital, Little Rock, AR, USA

Applications of Multiplex Molecular Imaging in Cancer

High Dimensional Imaging of Tumor Immune Infiltrates Using MIBI
Michael Angelo, MD, PhD, Stanford University, Palo Alto, CA, USA

8:30am - 9:45am

AMP Award for Excellence in Molecular Diagnostics: Presentation and Lecture

The Epigenetic Basis of Common Human Disease
Andrew P. Feinberg, MD, MPH, Johns Hopkins University of Medicine, Whiting School of Engineering, and Bloomberg School of Public Health, Baltimore, MD, USA


Friday, November 17, 2017


7:00am - 8:00am


Novel Technologies: Cool Toys for You Now and in the Future

Gene Expression Profiling During Infection Using Digital Barcoded Probe Technology
Wenjie Xu, PhD, NanoString Technologies, Seattle, WA, USA

Implementation of a Diagnostic Device Syndromic Disease Network
Lindsay Meyers, BSc, BioFire Diagnostics, LLC, Salt Lake City, Utah, USA

Introduction to Smarticles™ Technology: Potential Applications in Antimicrobial Stewardship
Michael Lewinski, PhD, Roche Molecular Systems, Inc., Pleasanton, CA, USA


Saturday, November 18, 2017


7:00am - 8:00am


Biorepositories in Precision Medicine

The Role of Biobanks in Precision Medicine Research and Care
Nazneen Aziz, PhD, Kaiser Permanente Research Bank, Oakland, CA, USA

The "All of Us" Research Program- Precision Medicine Initiative: One Million Cohort

Mine S. Cicek, PhD, Mayo Clinic, MN, USA

Platform Presentations of Selected Technical Topics Abstracts

TT92 - Successful Extraction of RNA from Archived Bone Marrow Aspirate Smears for Use in Targeted RNA Sequencing
Tamara Restrepo, BSc, Boston Children's Hospital, Boston, MA, USA

TT82 - High Performance Detection of Cancer Mutations from Circulating DNA Using Single Color Digital PCR
Christina Wood-Bouwens, Standford School of Medicine, Department of Oncology, Stanford, CA, USA

TT24 - Screening Circulating Nucleic Acids of Pancreatic Ductal Adenocarcinoma Using a Plasmonic Nanosensor
Amogha Tadimety, Dartmouth College, Hanover, NH, USA

TT76 - Engineering of Isogenic Cell Lines Using the CRISPR/Cas9 Technology and Precise Characterization of Low Allelic Frequency FFPE Cell Line Blocks for Use as Molecular Reference Standards
Andrew Hilmer, PhD, Applied Stem Cell, Milpitas, CA, USA

1:30pm - 3:00pm


Emerging Technology for Structural Variant Detection

Mate-Pair Sequencing in Cytogenetics
Nicole L. Hoppman, PhD, Mayo Clinic, Rochester, MN, USA

Digital Karyotyping and Complex Rearrangement Analysis with Sequencing at Single Molecule Resolution
Hanlee P. Ji, MD, Stanford University School of Medicine, Stanford, CA, USA

3:15pm - 4:45pm


Role of Genome Editing in Research and Therapy

Genome Editing with CRISPR-Cas Nucleases
J. Keith Joung, MD, PhD, Massachusetts General Hospital, Charlestown, MA, USA

Accelerating Prediction of Tumor Vulnerabilities Using Next-generation Cancer Models
Jesse S. Boehm, PhD, Broad Institute, Cambridge, MA, USA